A Simple Guide To The Sunshine Hormone (Vitamin D) Diagnosis of Deficiency Treatment And Related Conditions (A Simple Guide to Medical Conditions)
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Description
Vitamin D is a fat soluble vitamin hormone which increases the absorption and metabolism of calcium and phosphorous jointly with parathyroid glands.
People who are exposed to normal amounts of sunlight do not require vitamin D supplements because sunlight provides adequate vitamin D synthesis in the skin.
Hormone: The hormone is a chemical material produced in the body that controls and regulates the action of certain cells or organs.
Vitamins: The vitamin is an organic element in food that is required in very small quantity for development and for maintaining good health.
Vitamins are substances that are necessary for the function of the human body but are not produced by the body.
Vitamin D is formed in the body and has the same chemical structure as sex and adrenal hormones and hence it is considered a hormone rather than a vitamin
Alternative names for vitamin D
1. Calcitriol (or 1 25 dihydroxyvitamin D);
2. Ergocalciferol (vitamin D2);
3. Cholecalciferol (vitamin D3);
4. Calcidiol (25 hydroxyvitamin D).
Vitamin D is an active hormone produced by the kidneys that assists to manage the concentration of calcium in the blood and is very important for the formation of strong bones.
Vitamin D is in reality a hormone rather than a vitamin.
The body makes a large amount of the vitamin D it requires; only about 10% comes from the food.
The action of sunlight on the skin manufactures an inert substance called cholecalciferol which is transformed by the liver to the inert calcidiol in seven days.
Calcidiol is regarded as a good indicator of vitamin D levels and is the form that is normally measured by doctors.
This is later transformed in the kidneys by the enzyme 1α hydroxylase to calcitriol a secosteroid hormone that is the active form of vitamin D.
It can also be transformed into 24 hydroxycalcidiol in the kidneys through 24 hydroxylation.
The active form of vitamin D is manufactured primarily by the kidneys but there are also a number of other tissues in the body that activate vitamin D.
Excess cholecalciferol and calcidiol produced during the summer are stored in the body fat for use during the winter.
Vitamin D alters the action of bone cells and is essential for the development of new bone in children and adults.
It also controls the calcium levels in the blood by helping the body to take in calcium from food and by avoiding calcium loss from the kidneys.
With sun exposure the skin can provide the vitamin D the body requires.
Ultraviolet B (UVB) rays willingly transform cholesterol stored in the skin into vitamin D3 which is eventually transformed to the active form of vitamin D.
When adequate D3 is produced the skin ceases production making a vitamin D sun overdose not possible.
Vitamin D Deficiency is a medical disorder caused by the deficiency of the human of Vitamin D as a result of insufficient dietary intake or impaired absorption.
Insufficient vitamin D from sun exposure or dietary intake results in deficiency states
Severe vitamin D deficiency has serious results for bone health presenting as rickets in children and osteomalacia in adults.
Vitamin D deficiency is frequent in the elderly especially people who have dark skin and are not exposed to the sun
1. Poor exposure to sun light
2. Malabsorption of Vitamin D may occur in gluten enteropathy or post gastrectomy
3. Renal disease and anticonvulsant drugs may decrease the development of active metabolites of vitamin D
4. Increased catabolism from certain medicines;
5. In infants the minimal amount of vitamin D found in breast milk.
Treatment is by :
1. Sensible sun exposure between the hours of 10 am and 3 pm supplies vitamin D in the skin
2. Recommended dietary intake of vitamin D and calcium in fortified food
TABLE OF CONTENT
Introduction
Chapter 1 Vitamin D (Calciferol)
Chapter 2 Cause of Deficiency
Chapter 3 Symptoms
Chapter 4 Diagnosis
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